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The Antimicrobial Peptide Database (APD) contains 2387 antimicrobial peptides (227 bacteriocins, 6 protozoan antibacterial peptides, 12 fungal AMPs, 306 plant AMPs, and 1794 animal host defense peptides) with the following activity:
Antibacterial Peptides
Antiviral Peptides
Antifungal Peptides
Antiparasitic Peptides
Anticancer/tumor Peptides
Anti-protist Peptides
Insecticidal Peptides
Spermicidal Peptides
Anti-HIV-1 Peptides
AMPs with chemotactic activity
A manually curated database resource, whose peptide entries were collected based on a set of criteria (see About)

310 unique structures annotated and over 200 with coordinates deposited in the PDB can be rotated, zoomed, and viewed.

This database consists of a pipeline of search functions for you to search for peptide information using APD ID, peptide name, amino acid sequence, peptide motif, chemical modification, length, charge, hydrophobic content, PDB ID, 3D structure, methods for structural determination, peptide source organism, peptide family name, life domains (bacteria, protozoan, fungi, plants, animals), antimicrobial activities (see links above), synergistic effects, target microbes, molecular targets, mechanism of action, contributing authors, and year of publication.
In addition, you can access the APD Peptide Calculator here.

CITE: 1. Wang, G., Li, X. and Wang, Z. (2009) APD2: the updated antimicrobial peptide database and its application in peptide design. Nucleic Acids Research 37, D933-D937. Paper PDF
2. Wang, Z. and Wang, G. (2004) APD: the antimicrobial peptide database. Nucleic Acids Research 32, D590-D592.] Paper PDF

Last updated: April 2014 | Copyright 2003-2014 Dept of Pathology & Microbiology, UNMC, All Rights Reserved