Antimicrobial Peptide AP02554

     
 

APD ID:

AP02554

 
 

Name/Class:

Psalmopeotoxin II (PcFK2; U2-TRTX-Pc1a; spiders, arachnids, Chelicerata, arthropods, invertebrates, animals; 3S=S, UCSS1a )

 
 

Source:

venom, the Trinnidad chevron tarantula,Psalmopoeus cambridgei

 
 

Sequence:

RCLPAGKTCVRGPMRVPCCGSCSQNKCT

 
 

Length:

28

 
 

Net charge:

5

 
 

Hydrophobic residue%:

39%

 
 

Boman Index:

1.86 kcal/mol

 
 

3D Structure:

Bridge

 
 

SwissProt ID:

Reference ID: Ref  

 
 

Activity:

antiparasitic, Antimalarial,

 
 

Crucial residues:

 
 

Additional info:

APD analysis reveals that the sequence is 45.2% similar to plant Viba17. It inhibited P. falciparum at 1.15 uM. Provided by Xiuqing Wang.

 
       
 

Title:

Isolation and characterization of Psalmopeotoxin I and II: two novel antimalarial peptides from the venom of the tarantula Psalmopoeus cambridgei.

 
 

Author:

Choi SJ, Parent R, Guillaume C, Deregnaucourt C, Delarbre C, Ojcius DM, Montagne JJ, CÚlÚrier ML, Phelipot A, Amiche M, Molgo J, Camadro JM, Guette C.2004

 
 

Reference:

FEBS Lett. 2004 Aug 13;572(1-3):109-17. PubMed

 
       

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