Antimicrobial Peptide AP02518

     
 

APD ID:

AP02518

 
 

Name/Class:

Cm38 (scorpions, arachnids, Chelicerata, arthropods, invertebrates, animals; BWQ, UCLL1a?)

 
 

Source:

scorpion venom, Centruroides margaritatus

 
 

Sequence:

ARDGYIVDEKGCKFACFIN

 
 

Length:

19

 
 

Net charge:

0

 
 

Hydrophobic residue%:

47%

 
 

Boman Index:

1.53 kcal/mol

 
 

3D Structure:

Unknown

 
 

SwissProt ID:

Reference ID: Ref  

 
 

Activity:

Anti-Gram-,

 
 

Crucial residues:

 
 

Additional info:

Purified from a 2-step chromatographic method. Warning: only the N-terminal 19 amino acids are reported based on Edman degradation. 38.5% SIMILAR TO Brevinin-2-related peptide. Active against K. pneumoniae (MIC 64 uM). Also active in neurons.

 
       
 

Title:

Cm38: A New Antimicrobial Peptide Active Against Klebsiella pneumoniae is Homologous to Cn11

 
 

Author:

Duenas-Cuellar RA, Kushmerick C, Naves LA, Batista IF, Guerrero-Vargas JA, Pires OR Jr, Fontes W, Castro MS. 2015

 
 

Reference:

Protein Pept Lett. 2015;22(2):164-72. PubMed

 
       

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