Antimicrobial Peptide AP01700

     
 

APD ID:

AP01700

 
 

Name/Class:

Meucin-25 (antimalarial peptide; toxins; scorpions, arachnids, Chelicerata, arthropods, invertebrates, animals; ZZP, UCLL1a)

 
 

Source:

scorpion Mesobuthus eupeus

 
 

Sequence:

VKLIQIRIWIQYVTVLQMFSMKTKQ

 
 

Length:

25

 
 

Net charge:

4

 
 

Hydrophobic residue%:

52%

 
 

Boman Index:

0.43 kcal/mol

 
 

3D Structure:

Helix

 
 

Method:

CD

 
 

SwissProt ID:

Reference ID: Ref  

 
 

Activity:

antiparasitic, Antimalarial,

 
 

Crucial residues:

 
 

Additional info:

Active against rodent malaria P. berghei and human malaria P. falciparum. Helix in TFE.

 
       
 

Title:

Characterization of two linear cationic antimalarial peptides in the scorpion Mesobuthus eupeus

 
 

Author:

Gao B, Xu J, Rodriguez Mdel C, Lanz-Mendoza H, Hernández-Rivas R, Du W, Zhu S2010

 
 

Reference:

Biochimie. 2010 Apr;92(4):350-9

 
       

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