Antimicrobial Peptide AP01465

     
 

APD ID:

AP01465

 
 

Name/Class:

Lasioglossin LL-I (XXA; insects, arthropods, invertebrates, animals)

 
 

Source:

the Eusocial Bee Lasioglossum laticeps

 
 

Sequence:

VNWKKVLGKIIKVAK

 
 

Length:

15

 
 

Net charge:

6

 
 

Hydrophobic residue%:

53%

 
 

Boman Index:

0.16 kcal/mol

 
 

3D Structure:

Helix

 
 

Method:

NMR

 
 

SwissProt ID:

Reference ID: Ref  

 
 

Activity:

Anti-Gram+ & Gram-, Anticancer

 
 

Crucial residues:

N-terminal 5 residues and amidation

 
 

Additional info:

Active against B. subtilis, S. aureus, P. aeruginosa, and E. coli. Low hemolytic toxicity. NMR studies were conducted in TFE.

 
       
 

Title:

Lasioglossins: Three Novel Antimicrobial Peptides from the Venom of the Eusocial Bee Lasioglossum laticeps (Hymenoptera: Halictidae).

 
 

Author:

Cerovský V, Budesínský M, Hovorka O, Cvacka J, Voburka Z, Slaninová J, Borovicková L, Fucík V, Bednárová L, Votruba I, Straka J.2009

 
 

Reference:

Chembiochem. 2009 Aug 17;10(12):2089-99. PubMed.

 
       

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