Antimicrobial Peptide AP01389“>013892582.73 %100.0 %AVP
     
 

APD ID:

AP01389

 
 

Name/Class:

Dermaseptin 01 (DRS-01, DRS 01; DRS01; DS-01; DS 01; DShypo 05; XXA; UCLL1c; frog, amphibians, animals; ZZP)

 
 

Source:

Phyllomedusa oreades, Brazil, South America; also Phyllomedusa hypochondrialis

 
 

Sequence:

GLWSTIKQKGKEAAIAAAKAAGQAALGAL

 
 

Length:

29

 
 

Net charge:

4

 
 

Hydrophobic residue%:

55%

 
 

Boman Index:

-0.09 kcal/mol

 
 

3D Structure:

Unknown

 
 

SwissProt ID:

Reference ID: Ref  

 
 

Activity:

Anti-Gram+ & Gram-, Antiparasitic,

 
 

Crucial residues:

 
 

Additional info:

C-terminal NH2. Active against E. coli, S. aureus, and X. axonopodis. Also found in Phyllomedusa hypochondrialis (Brand GD et al., 2006). Found in multiple species. Updated 12/2015.

 
       
 

Title:

Dermaseptins from Phyllomedusa oreades and Phyllomedusa distincta. Anti-Trypanosoma cruzi activity without cytotoxicity to mammalian cells.

 
 

Author:

Brand GD, Leite JR, Silva LP, Albuquerque S, Prates MV, Azevedo RB, Carregaro V, Silva JS, Sá VC, Brandão RA, Bloch C Jr.2002

 
 

Reference:

J Biol Chem. 2002 Dec 20;277(51):49332-40

 
       

Close this window