Antimicrobial Peptide AP01209“>012091983.32 %97.02 %AVP
     
 

APD ID:

AP01209

 
 

Name/Class:

Retrocyclin-3 (RC3; theta-defensin; synthetic, 3S=S, Cys-rich; UCBB1b; XXC, BBS, lectin)

 
 

Source:

Derived from a silent gene (pre-stop)

 
 

Sequence:

RICRCICGRRICRCICGR

 
 

Length:

18

 
 

Net charge:

6

 
 

Hydrophobic residue%:

55%

 
 

Boman Index:

3.34 kcal/mol

 
 

3D Structure:

Bridge

 
 

SwissProt ID:

Reference ID: Ref  

 
 

Activity:

Antiviral, Anti-toxin,

 
 

Crucial residues:

 
 

Additional info:

MOA: It binds to gp120 and CD4, thereby inhibiting HIV entry.

 
       
 

Title:

Activity of alpha- and theta-defensins against primary isolates of HIV-1.

 
 

Author:

Wang W, Owen SM, Rudolph DL, Cole AM, Hong T, Waring AJ, Lal RB, Lehrer RI.

 
 

Reference:

J Immunol. 2004 Jul 1;173(1):515-20

 
       

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