Antimicrobial Peptide AP00782“>007822064.63 %100.0 %AVP
     
 

APD ID:

AP00782

 
 

Name/Class:

NRC-06 (NRC-6; XXA, fish, animals; UCLL1c)

 
 

Source:

winter flounder 4 1.1, Pleuronectes americanus

 
 

Sequence:

GWGSIFKHGRHAAKHIGHAAVNHYL

 
 

Length:

25

 
 

Net charge:

4

 
 

Hydrophobic residue%:

40%

 
 

Boman Index:

0.97 kcal/mol

 
 

3D Structure:

Unknown

 
 

SwissProt ID:

Reference ID: Ref  

 
 

Activity:

Anti-Gram+ & Gram-, Antifungal, Anti-MRSA,

 
 

Crucial residues:

 
 

Additional info:

C-terminal NH2. Active against A. salmonicida 99-1, A. salmonicida 97-4, S. enterica serovar Typhimurium MS7953s (MIC 4 uM), S. enterica serovar Typhimurium 14028s (MIC 64 uM), P. aeruginosa K799 (MIC 16 uM), P. aeruginosa Z61, E. coli CGSC4908, E. coli UB1005 (MIC 4 uM), E. coli DC2 (MIC 2 uM), MRSA C623, C. albicans C627 (MIC 32 uM).

 
       
 

Title:

Novel antimicrobial peptides derived from flatfish genes

 
 

Author:

Patrzykat A, Gallant JW, Seo JK, Pytyck J, Douglas SE.2003

 
 

Reference:

Antimicrob Agents Chemother. 2003 Aug;47(8):2464-70.PubMed. .

 
       

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