Antimicrobial Peptide AP00779“>007792368.28 %94.22 %AVP
     
 

APD ID:

AP00779

 
 

Name/Class:

NRC-03 (NRC-3; XXA, fish, animals; UCLL1c)

 
 

Source:

winter flounder 1a-1, Pleuronectes americanus

 
 

Sequence:

GRRKRKWLRRIGKGVKIIGGAALDHL

 
 

Length:

26

 
 

Net charge:

9

 
 

Hydrophobic residue%:

38%

 
 

Boman Index:

2.53 kcal/mol

 
 

3D Structure:

Unknown

 
 

SwissProt ID:

Reference ID: Ref  

 
 

Activity:

Anti-Gram+ & Gram-, Antifungal, Anti-MRSA,

 
 

Crucial residues:

 
 

Additional info:

C-terminal NH2. Highly active against A. salmonicida 99-1, A. salmonicida 97-4, S. enterica serovar Typhimurium MS7953s, S. enterica serovar Typhimurium 14028s, P. aeruginosa K799, P. aeruginosa Z61, E. coli CGSC4908, E. coli UB1005, E. coli DC2, S. epidermidis C621, MRSA C623, C. albicans C627 (MIC 1-8 uM).

 
       
 

Title:

Novel antimicrobial peptides derived from flatfish genes

 
 

Author:

Patrzykat A, Gallant JW, Seo JK, Pytyck J, Douglas SE.2003

 
 

Reference:

Antimicrob Agents Chemother. 2003 Aug;47(8):2464-70.PubMed.

 
       

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