Antimicrobial Peptide AP00588

     
 

APD ID:

AP00588

 
 

Name/Class:

Brevinin-1TSa (XXA; UCLL1c; frog, amphibians, animals)

 
 

Source:

Rana tsushimensis, Asia

 
 

Sequence:

FLGSIVGALASALPSLISKIRN

 
 

Length:

22

 
 

Net charge:

3

 
 

Hydrophobic residue%:

54%

 
 

Boman Index:

-0.36 kcal/mol

 
 

3D Structure:

Unknown

 
 

SwissProt ID:

Reference ID: Ref  

 
 

Activity:

Anti-Gram+ & Gram-, Antifungal, candidacidal, Anti-MRSA, Hemolytic,

 
 

Crucial residues:

 
 

Additional info:

Much less active than 2TSa (AP587). active against S. epidermidis RP62A (MIC 12.5 uM), E. coli ATCC25922, S. aureus NCTC 8325, MRSA T7/20 (MIC 25 uM), E. cloacae HNTCC 5300, P. aeruginosa ATCC 27853, E. faecalis ATCC 29212, Streptococcus group B HNTCC 80130, C. albicans ATCC 90028 (MIC 50 uM), HC50 12 uM. Updated 5/2020.

 
       
 

Title:

Antimicrobial peptides from the skin of the Tsushima brown frog Rana tsushimensis

 
 

Author:

Conlon JM, et al., Iwamuro S.2006

 
 

Reference:

Comp. Biochem. Physiol. part C, 2006; 143: 42-49. PubMed.

 
       

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