Antimicrobial Peptide AP00159

     
 

APD ID:

AP00159

 
 

Name/Class:

Dermaseptin-S3 (DRS-S3; Dermaseptin S3, DRS S3, DS3, UCLL1; frog, amphibians, animals; ZZP)

 
 

Source:

Sauvage's leaf frog, Phyllomedusa sauvagii, South America

 
 

Sequence:

ALWKNMLKGIGKLAGKAALGAVKKLVGAES

 
 

Length:

30

 
 

Net charge:

5

 
 

Hydrophobic residue%:

53%

 
 

Boman Index:

-0.25 kcal/mol

 
 

3D Structure:

Helix

 
 

SwissProt ID:

SwissProt ID: P80279  Go to SwissProt

 
 

Activity:

anti-Gram+ & Gram-, antifungal, antiparasitic, Antimalarial,

 
 

Additional info:

Active against P. falciparum. Based on the primary structure, it can be fitted to a class L amphipathic alpha helix which places all K on the polar face.

 
       
 

Title:

Isolation and structure of novel defensive peptides from frog skin.

 
 

Author:

Mor A, Nicolas P.1994

 
 

Reference:

Eur. J. Biochem. 1994; 219:145-154.PubMed.

 
       

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