Antimicrobial Peptide AP00136“>001362683.34 %100.0 %AVP
     
 

APD ID:

AP00136

 
 

Name/Class:

Crabrolin (XXA; insects,arthropods, invertebrates, animals)

 
 

Source:

the European hornet, Vespa crabro

 
 

Sequence:

FLPLILRKIVTAL

 
 

Length:

13

 
 

Net charge:

3

 
 

Hydrophobic residue%:

69%

 
 

Boman Index:

-1.17 kcal/mol

 
 

3D Structure:

Helix

 
 

Method:

NMR

 
 

SwissProt ID:

SwissProt ID: P01518  Go to SwissProt

 
 

Activity:

Anti-Gram+ & Gram-, Hemolytic,

 
 

Additional info:

This peptide forms an amphipathic helix in a membrane-mimetic TFE (50%) with residues 3-11 being helical (Aschi M et al., 2017), providing a basis for its activity. Updated 6/2018.

 
       
 

Title:

Isolation and characterization of two new peptides, mastoparan C and crabrolin, from the venom of the European hornet, Vespa crabro.

 
 

Author:

Argiolas A, Pisano JJ.1984

 
 

Reference:

J Biol Chem. 1984 Aug 25;259(16):10106-11. PubMed.

 
       

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