Antimicrobial Peptide AP0006“>00061759.04 %95.98 %AVP
     
 

APD ID:

AP00006

 
 

Name/Class:

Apidaecin IA (Pro-rich; insects, arthropods, invertebrates,animals; BBL; VIHNN)

 
 

Source:

honeybee, Apis mellifera L.

 
 

Sequence:

GNNRPVYIPQPRPPHPRI

 
 

Length:

18

 
 

Net charge:

4

 
 

Hydrophobic residue%:

16%

 
 

Boman Index:

2.97 kcal/mol

 
 

3D Structure:

Rich

 
 

SwissProt ID:

SwissProt ID: P35581  Go to SwissProt

 
 

Activity:

Anti-Gram-,

 
 

Additional info:

Rich in P. Active against G+ bacteira B. negaterium (MIC 25 ug/ml), but mainly G- bacteria E. coli, S. typhimurium, E. salicis (MIC 0.1 ug/ml or less) (see AP1210 for ref). Also active against A. tumefaciens Gembloux A, E. salicis NCPPB 2530, E. coli NCTC 9001 (MIC <1 ug/ml), E. coli NCTC 9001* (1-5 ug/ml), E. coli K514 (MIC 25-50 ug/ml), P. syringae pv. tomamta NCPPB 1105 (MIC <1 ug.ml), and Gram-positive bacteria B. megaterium OMB 1551 (MIC 25-50 ug/ml), B. alvei LPM 6922 (50-100 ug/ml), and M. luteus (M. lysodeikticus) LMG 4050 (MIC 25-50 ug/ml) (see ref. for AP00002). Updated 5/2014; 7/2014.

 
       
 

Title:

Apidaecins: antibacterial peptides from honeybees.

 
 

Author:

Casteels P, Ampe C, Jacobs F, Vaeck M, Tempst P.1989

 
 

Reference:

EMBO J. 1989 Aug;8(8):2387-91. PubMed.

 
       

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