| |
APD ID: |
AP00027 |
|
| |
Name: |
LfcinB6 (hexapeptide; XXA; synthetic) |
|
| |
Source: |
Bos taurus |
|
| |
Sequence: |
RRWQWR |
|
| |
Length: |
6 |
|
| |
Structure: |
Rich |
|
| |
Method: |
NMR |
|
| |
Additional info: |
Corresponding to residues 4-9 of Lactoferrin B (PDB 1LFC). 3D structure in SDS micelles. free LfcinB6 did not kill T-leukemia or breast cancer cells but LfcinB6 was strongly cytotoxic when delivered to the cytosolic compartment by fusogenic liposomes (Richardson A 2009 Biochem Biophys Res Commun. 2009 Aug 21). |
|
| |
Activity: |
Gram+ & Gram-, Virus, Fungi, Cancer cells |
|
| |
Net charge: |
3 |
|
| |
Hydrophobic residue%: |
33% |
|
| |
Boman Index: |
7.6 kcal/mol |
|
| |
|
|
|
| |
SwissProt ID: |
Reference ID:
Ref |
|
| |
Reference: |
Biochem. Cell Biol. 2002; 80:49-63 |
|
| |
Author: |
Vogle HJ, Schibli JD, Jing W., Epand FR, Epand RM. |
|
| |
Title: |
Towards a structure-function analysis of bovine lactoferricin and related tryptophan and arginine containing peptides |
|
| |
|
|
|