Antimicrobial Peptide AP00025

     
 

APD ID:

AP00025

 
 

Name/Class:

Alloferon 1 (Alloferon-1; Gly-rich, His-rich, insects, arthropods, invertebrates, animals; Derivatives: ZL-2)

 
 

Source:

Blow fly Calliphora vicina

 
 

Sequence:

HGVSGHGQHGVHG

 
 

Length:

13

 
 

Net charge:

4

 
 

Hydrophobic residue%:

15%

 
 

Boman Index:

1.13 kcal/mol

 
 

3D Structure:

Rich

 
 

SwissProt ID:

SwissProt ID: P83412  Go to SwissProt

 
 

Activity:

antiviral, Cancer cells

 
 

Additional info:

Alloferon inhibited the the herpes simplex virus (HSV) multiplication (Kuczer et al. 2011). ZL-2 (sequence: HGVSGHGQHGTHG) was generated by sequence mutations (Tu J et al., 2015). Updated 12/2017.

 
       
 

Title:

Novel antiviral and antitumoral peptides from insects.

 
 

Author:

Chernysh S, Kim SI, Bekker G, Pleskach VA, Filatova NA, Anikin VB, Platonov VG, Bulet P.2002

 
 

Reference:

Proc Natl Acad Sci U S A 2002; 99 (20):12628-32. PubMed.

 
       

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