Antimicrobial Peptide AP00017

     
 

APD ID:

AP00017

 
 

Name/Class:

Aurein 2.4 (XXA, UCLL1c; frog, amphibians, animals)

 
 

Source:

Southern bell frog Litoria aurea or Litoria raniformis, Australia

 
 

Sequence:

GLFDIVKKVVGTLAGL

 
 

Length:

16

 
 

Net charge:

2

 
 

Hydrophobic residue%:

56%

 
 

Boman Index:

-1.06 kcal/mol

 
 

3D Structure:

Unknown

 
 

SwissProt ID:

SwissProt ID: P82391  Go to SwissProt

 
 

Activity:

anti-Gram+ & Gram-, antifungal, Cancer cells

 
 

Additional info:

Active against B. cereus, M. luteus, S. aureus, S. epidermidis, S. uberis (MIC 25 ug/ml) and L. lactis (MIC 12 ug/ml) (provided by Chunfeng Wang). C-terminal NH2; Contains: Aurein 2.4.1 (residue 3 to 16). The sequence was validated in 2008. Found in multiple species. Updated 9/2017.

 
       
 

Title:

The antibiotic and anticancer active aurein peptides from the australian bell frogs Litoria aurea and Litoria raniformis the solution structure of aurein 1.2.

 
 

Author:

Rozek T, Wegener KL, Bowie JH, Olver IN, Carver JA, Wallace JC, Tyler MJ.2000

 
 

Reference:

Eur J Biochem. 2000 Sep;267(17):5330-41. PubMed.

 
       

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