Detailed Information About Peptide AP00016

     
 

APD ID:

AP00016

  
 

Name:

Aurein 2.3 (XXA, frog, amphibians, animals)

  
 

Source:

Southern bell frog

  
 

Sequence:

GLFDIVKKVVGAIGSL

  
 

Length:

16

  
 

Structure:

Helix

 
 

Method:

NMR

  
 

Additional info:

C-terminal NH2. NMR: Biophys. J 2007; 92, 2854-64.

  
 

Crucial residues:

Gain anticancer activity if change I13 to F (change to P82392)

  
 

Activity:

Gram+ & Gram-, Fungi, Cancer cells

  
 

Net charge:

1

  
 

Hydrophobic residue%:

56%

  
 

Boman Index:

-1.01 kcal/mol

  
       
 

SwissProt ID:

SwissProt ID: P82390  Go to SwissProt

 
 

Reference:

Eur. J. Biochem. 267:5330-5341(2000)

  
 

Author:

Rozek T, Wegener KL, Bowie JH, Olver IN, Carver JA, Wallace JC, Tyler MJ.

  
 

Title:

The antibiotic and anticancer active aurein peptides from the australian bell frogs Litoria aurea and Litoria raniformis the solution structure of aurein 1.2.

  
       

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