Detailed Information About Peptide AP00005

     
 

APD ID:

AP00005

 
 

Name:

Andropin (insect, fly, invertebrates, animals)

 
 

Source:

Fruit fly, Drosophila melanogaster

 
 

Sequence:

VFIDILDKVENAIHNAAQVGIGFAKPFEKLINPK

 
 

Length:

34

 
 

Structure:

Unknown

 
 

Additional info:

Andropin is less fungicidal than the cecropins, and Drosophila cecropin A is somewhat more potent than cecropin B (Insect Biochem Mol Biol. 1999;29:965-72). Along with other antimicrobial proteins, this peptide sterilizes the production system of insects and protects sperms from being infected by bacteria (J Insect Physiol. 2001 Jun;47(6):617-622). It appears that a similar protecting antimicrobial peptide, ALL-38, exists in human genital systems (see APD entry 624).

 
 

Activity:

Gram+,

 
 

Net charge:

1

 
 

Hydrophobic residue%:

50%

 
 

Boman Index:

0.55 kcal/mol

 
       
 

SwissProt ID:

SwissProt ID: P21663  Go to SwissProt

 
 

Reference:

EMBO J. 1991; 10:163-169

 
 

Author:

Samakovlis, C., Kylsten, P., Kimbrell, DA., Engstroem, A., Hultmark, D.

 
 

Title:

The andropin gene and its product, a male-specific antibacterial peptide in Drosophila melanogaster.

 
       

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