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Contact

Dr. Gus Wang
Eppley Institute
University of Nebraska Medical Center
Phone: 402-559-4176
Fax: 402-559-4651
gwang@unmc.edu

Omaha NMR: Meeting | Instruments
Selected Publications

Wang, G.*, Keifer, P.A., Peterkofsky, A. (2003) Solution structure of the N-terminal amphitropic domain of the Escherichia coli glucose-spec ific enzyme IIA in membrane-mimetic micelles. Protein Sci.12, 1087-1096. PDB entry: 1O53; BMRB entry: 5708.

Wang, Z., Wang*, G. (2004) APD: the Antimicrobial Peptide Database. Nucleic Acids Res. 32, D590-D592.
This is the paper for your citation if you have found useful info from the database.

Wang, G.*, Keifer, P.A., Peterkofsky, A. (2004) Short-chain diacyl phosphatidylglycerols: which one to choose for NMR structural determination of a membrane-associated peptide from Escherichia coli? Spectroscopy 18, 257-264.

Keifer, P., Peterkofsky, A., Wang*, G. (2004) Effects of detergent alkyl chain length and chemical structure on the properties of a micelle-boun d bacterial membrane targeting peptide. Anal. Biochem. 331, 33-39.

Wang, G.*, Li, Y., Li, X. (2005) Correlation of three-dimensional structures with the antibacterial activity of a group of peptides designe d based on a non-toxic bacterial membrane anchor. J. Biol Chem. 280, 5803-5811. PDB entries: 1VM2, 1VM3, 1VM4, and 1VM5.

Wang, G.* (2006) Structural biology of antimicrobial peptides by NMR spectroscopy . Current Organic Chemistry 10, 569-581. An invited review.

Li, Y., Li, X., Wang*, G. (2006) Cloning, expression, isotope labeling, and purification of human antimicrobial peptide LL-37 in Escherichia coli for NMR studies. Protein Exp. Purif. 47, 498-505.

Li, X., Li, Y., Peterkofsky, A., Wang, G.* (2006) NMR studies of aurein 1.2 analogs. Biochim Biophys Acta 1758, 1203-1214.

Li, X., Li, Y., Han, H., Miller, D.W., Wang, G.* (2006) Solution structures of human LL-37 fragments and NMR-based identification of a minimal mem brane-targeting antimicrobial and anticancer region. J. Am. Chem. Soc. 128, 5776-85.

Wang, G.* (2007) Tool developments for structure-function studies of host defense peptides. Protein Peptide Letters 14, 57-69. An invited review.

Li, et al., Wang, G.* (2007) A novel method for purifying recombinant human host defense cathelicidin LL-37 by utilizing its inherent property of aggregation. Protein Expr. Purif. 54, 157-165.

Li, Y., Li X., Wang, G.* (2007) On-resin cleavage of bacterially expressed fusion proteins for purification of active recombinant peptides SK-29, KR-20, LL-29, and LL-23 (discovered) from human sweat or skin Protein Expression & Purification. 55, 395-405.

Wang, G.* (2007) Determination of solution structure and lipid micelle location of an engineered membrane peptide by using one NMR experiment and one sample. Biochim. Biophys. Acta 1768, 3271-3281.

Wang, G.* (2008) NMR of membrane-associated peptides and proteins. Current Protein Peptide Science 9, 50-69. An invited review.

Wang, G.* (2008) NMR studies of a model antimicrobial peptide in the micelles of SDS, dodecylphosphocholine, or dioctanoylphosphatidylglycerol . The Open Magnetic Resonance Journal 1, 9-15

Wang, G.*, Waston, K., and Buckheit, R., Jr. (2008) Anti-Human immunodeficiency virus type 1 (HIV-1) activities of antimicrobial peptides derived from human and bovine cathelicidins. Antimicrobal Agents Chemotherapy 52, 3438-3440.
* Corresponding author.
Designed by Sophie Wang | Last updated: Sept 2008 | Copyright 2003 & 2008 Eppley Institute, UNMC All Rights Reserved
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