The APD2 - Contact Info


		Contact Guangshun Wang, Ph.D. Eppley Institute University of Nebraska Medical Center Phone: 402-559-4176 Fax: 402-559-4651 gwang@unmc.edu Omaha NMR: Meeting \| Instruments

	Selected Publications Wang, Z., Wang, G. (2004)* APD: the Antimicrobial Peptide Database. Nucleic Acids Res. 32, D590-D592. This is the paper for your citation if you have found useful info from the database. Wang, G., Keifer, P.A., Peterkofsky, A. (2004)* Short-chain diacyl phosphatidylglycerols: which one to choose for NMR structural determination of a membrane-associated peptide from Escherichia coli? Spectroscopy 18, 257-264. Keifer, P., Peterkofsky, A., Wang, G. (2004)* Effects of detergent alkyl chain length and chemical structure on the properties of a micelle-boun d bacterial membrane targeting peptide. Anal. Biochem. 331, 33-39. Wang, G., et al., Li, X. (2005)* Correlation of three-dimensional structures with the antibacterial activity of a group of peptides designe d based on a non-toxic bacterial membrane anchor. J. Biol Chem. 280, 5803-5811. PDB entries: 1VM2, 1VM3, 1VM4, and 1VM5. Wang, G.* (2006) Structural biology of antimicrobial peptides by NMR spectroscopy . Current Organic Chemistry 10, 569-581. An invited review. Li, X., et al., Peterkofsky, A., Wang, G.*(2006) NMR studies of aurein 1.2 analogs. Biochim Biophys Acta 1758, 1203-1214. Li, X., et al., Han, H., Miller, D.W., Wang, G.* (2006) Solution structures of human LL-37 fragments and NMR-based identification of a minimal mem brane-targeting antimicrobial and anticancer region. J. Am. Chem. Soc. 128, 5776-85. Wang, G.* (2007) Tool developments for structure-function studies of host defense peptides. Protein Peptide Letters 14, 57-69. An invited review. Wang, G.* (2007) Determination of solution structure and lipid micelle location of an engineered membrane peptide by using one NMR experiment and one sample. Biochim. Biophys. Acta 1768, 3271-3281. Wang, G.* (2008) NMR of membrane-associated peptides and proteins. Current Protein Peptide Science 9, 50-69. An invited review. Wang, G.* (2008) NMR studies of a model antimicrobial peptide in the micelles of SDS, dodecylphosphocholine, or dioctanoylphosphatidylglycerol . The Open Magnetic Resonance Journal 1, 9-15 Wang, G., Waston, K., and Buckheit, R., Jr. (2008)* Anti-Human immunodeficiency virus type 1 (HIV-1) activities of antimicrobial peptides derived from human and bovine cathelicidins. Antimicrobal Agents Chemotherapy 52, 3438-3440. Wang, G.* (2008) Structures of human host defense cathelicidin LL-37 and its smallest antimicrobial peptide KR-12 in lipid micelles. J. Biol. Chem. 283, 32637-32643. Wang, G., Li, X., Wang, Z. (2009)* APD2: the updated antimicrobial peptide database and its application in peptide design. Nucleic Acids Research 37, D933-D937. Published online Oct. 28, 2008. An invited article. Wang, G.* (2009) Structure, dynamics and mapping of membrane-binding residues of micelle-bound antimicrobial peptides by natural abundance 13C NMR spectroscopy.Biochim. Biophys. Acta In press. Epand, R.F., Wang, G., Berno, B, Epand, R.M. (2009) Lipid clustering explains the antimicrobial activity of fragments of the human cathelicidin LL-37. Antimicrob. Agents Chemother. 53, 3705-3714. * Corresponding author.

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